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The Resource Midlife in the United States (MIDUS Refresher): Biomarker Project, 2012-2016

Midlife in the United States (MIDUS Refresher): Biomarker Project, 2012-2016

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Midlife in the United States (MIDUS Refresher): Biomarker Project, 2012-2016
Title
Midlife in the United States (MIDUS Refresher): Biomarker Project, 2012-2016
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Summary
These data are being released in BETA version to facilitate early access to the study for research purposes. This collection has not been fully processed by NACDA or ICPSR at this time; the original materials provided by the principal investigator were minimally processed and converted to other file types for ease of use. As the study is further processed and given enhanced features by ICPSR, users will be able to access the updated versions of the study. Please report any data errors or problems to user support and we will work with you to resolve any data related issues. The MIDUS Refresher study Survey (2011-2014 <a href = "https://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/36532">ICPSR 36532</a>) recruited a national probability sample of 3,577 adults, aged 25 to 74, designed to replenish the original MIDUS 1 baseline cohort and paralleling the five decadal age groups of the MIDUS 1 baseline survey (<a href="https://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/2760">ICPSR 2760</a>). The MIDUS Refresher survey employed the same comprehensive assessments as those assembled on the core longitudinal MIDUS sample, but with additional questions about impacts of the economic recession of 2008-09. The MIDUS Refresher Biomarker study (2012-2016) obtained data from 863 respondents (n=746 Main sample, n=117 African Americans from Milwaukee) who completed the MIDUS Refresher Survey. The purpose of the Refresher Biomarker Project (Project 4) parallels that of the MIDUS 2 Biomarker project (<a href="https://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/29282">ICPSR 29282</a>), which collected comprehensive biological assessments on a subsample of MIDUS respondents, thus facilitating analyses that integrate behavioral and psychosocial factors with biological regulation/dysregulation, broadly defined. The aim was to use such data to explicate biopsychosocial pathways that contributed to diverse health outcomes. A further theme was to examine period effects on health (mental and physical) related to the economic recession by comparing the pre-recession MIDUS sample with the post-recession MIDUS Refresher sample. A further objective of the MIDUS Refresher sample was to strengthen cross-project analyses by increasing the sample sizes available for testing hypotheses regarding the interplay of key factors (e.g., socioeconomic status, gender, psychosocial factors, biological factors) in mid- and later-life health. Biomarker data collection was carried out at hypothalamic-pituitary-adrenal axis, the autonomic nervous system, the immune system, cardiovascular system, musculoskeletal system, antioxidants, and three General Clinical Research Centers (at UCLA, University of Wisconsin, and Georgetown University). The biomarkers reflect functioning of the metabolic processes. Our specimens (fasting blood draw, 12-hour urine, saliva) allowed for assessment of multiple indicators within these major systems. The protocol also included assessments by clinicians or trained staff, including vital signs, morphology, functional capacities including 3 dimensional gait analysis, bone densitometry, body composition, ankle brachial index, medication usage, and a physical exam. Project staff obtained indicators of heart-rate variability, beat to beat blood pressure, respiration, and salivary cortisol assessments during an experimental protocol that included both a cognitive and orthostatic challenge. Finally, to augment the self-reported data collected in Survey (Project 1), participants completed a medical history, self-administered questionnaire, and self-reported sleep assessments. For respondents at one site (UW-Madison), objective sleep assessments were also obtained with an Actiwatch(R) activity monitor
http://library.link/vocab/creatorName
Weinstein, Maxine
http://library.link/vocab/relatedWorkOrContributorName
  • Ryff, Carol D.
  • Seeman, Teresa E.
Label
Midlife in the United States (MIDUS Refresher): Biomarker Project, 2012-2016
Instantiates
Publication
Note
  • 2012-10--2016-08
  • 36901
Control code
ICPSR36901.v4
Governing access note
Access restricted to subscribing institutions
Label
Midlife in the United States (MIDUS Refresher): Biomarker Project, 2012-2016
Publication
Note
  • 2012-10--2016-08
  • 36901
Control code
ICPSR36901.v4
Governing access note
Access restricted to subscribing institutions

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